■ 教育工作经历 1）1990.09-1994.07，南开大学生命科学院，学士 2009.05-2014.02，瑞典卡罗林斯卡医学院肿瘤病例系，博士 2）1994.07-2002.11，江中制药厂北京药物研究所，工程师 2002.12-2007.01，北京宝赛生物技术有限公司，技术总工 2007.02-2007.11，北京科美东雅生物技术有限公司，政府事务与市场部 2014.03-2015.08，瑞典卡罗林斯卡医学院肿瘤研究中心，博士后 2015.09-2018.12，天津医科大学基础医学院，讲师 2019.01- 今，天津医科大学基础医学院，副教授 ■ 学术交流经历(国内外重要学术会议、讲学、访问) 2021.05，厦门大学（交流访学） 2013.11，澳大利亚布里斯班，大会口头报告（全球皮肤癌研究进展大会） 2012.10，德国柏林，大会口头报告（第6届国际乳头瘤病毒，多瘤病毒和紫外线辐射等相关皮肤癌会议） 多次参加国际及国内RNA、肿瘤等相关领域学术年会，进行墙报展示交流 ■ 学术与社会兼职 无。 ■ 课题研究 回国后主持国家自然科学基金面上项目、天津市自然科学基金面上项目各1项，参与天津市自然科学基金项目及天津市卫生行业重点攻关项目各1项；攻读博士与博士后工作期间，分别主持科研课题各1项（Karolinska Institutets Research Foundation Grant和Robert Lundbergs minnesstiftelse），参与科研课题多项。 ■ 核心刊物论文发表 作为通讯作者目前在投SCI研究论文2篇； 1. Satendra Kumar*, Hong Xie*, Hao Shi, Jiwei Gao, C. Christofer Juhlin, Viveca Bjornhagen, Anders Hoog, Linkiat Lee, Catharina Larsson, Weng-Onn Lui. Merkel cell polyomavirus oncoproteins induce microRNAs that suppress multiple autophagy genes, Int J Cancer. 2020; 146(6): 1652-1666. 2. Satendra Kumar*, Hong Xie*, Patrick Scicluna, Linkiat Lee, Viveca Bjornhagen, Anders Hoog, Catharina Larsson, Weng-Onn Lui. miR-375 regulation of LDHB plays distinct roles in polyomavirus-positive and -negative Merkel cell carcinoma, Cancers (Basel), 2018; 10(11): 443. 3. Hong Xie, Ingrid Norman, Anders Hjerpe, Tomislav Valdic, Catharina Larsson, Weng-Onn Lui, Ellinor Östensson, Sonia Andersson. Evaluation of microRNA-205 expression as a potential triage marker for patients with low-grade squamous intraepithelial lesions. Oncol Lett. 2017; 13(5): 3586-3598. 4. Hong Xie#, Linkiat Lee, Patrick Scicluna, Ersen Kawak, Catharina Larsson, Rickard Sandberg, Weng-Onn Lui#. Novel functions and targets of miR-944 in human cervical cancer cells. Int J Cancer. 2015; 136(5): E230-241. 5. Hong Xie#, Linkiat Lee, Stefano Caramuta, Anders Höög, Nanna Browaldh, Viveca Björnhagen, Catharina Larsson, Weng-Onn Lui#. microRNA expression patterns related to Merkel cell polyomavirus infection in human merkel cell carcinoma. J Invest Dermatol, 2014; 134(2): 507-517. 6. Hong Xie*, Tiantian Liu*, Na Wang, Viveca Björnhagen, Anders Höög, Catharina Larsson, Weng-Onn Lui, Dawei Xu. TERT promoter mutations and gene amplification: promoting TERT expression in Merkel cell carcinoma. Oncotarget. 2014; 5(20): 10048-10057. 7. Hong Xie#, Yungang Zhao, Stefano Caramuta, Catharina Larsson, Weng-Onn Lui#. miR-205 expression promotes cell proliferation and migration of human cervical cancer cells. PLoS ONE. 2012; 7(10): e46990. 8. Xiaoqing Zhao, Lu Sun, Ting Mu, Jianying Yi, Chaoqun Ma, Hong Xie, Min Liu, Hua Tang. An HBV-encoded miRNA activates innate immunity to restrict HBV replication. J Mol Cell Biol, 2020, 12(4): 263-276. 9. Jianying Yi*, Yajie Fan*, Le Zhang*, Hong Wang, Ting Mu, Hong Xie, Huijie Gao, Min Liu, Shengpin Li, Hua Tang. miR-HCC2 up-regulates BAMBI and ELMO1 expression to facilitate the proliferation and EMT of hepatocellular carcinoma cells. J Cancer, 2019; 10(15):3407-3419. 10. Xinyan Miao, Mohammed Ferdous-Ur Rahman, Lei Jiang, Yanan Min, Shuai Tan, Hong Xie, Linkiat Lee, Miao Wang, Rickard E. Malmström, Weng-Onn Lui, Nailin Li. Thrombin-reduced miR-27b attenuates platelet angiogenic activities in vitro via enhancing platelet synthesis of anti-angiogenic thrombospondin-1. J Thromb Haemost. 2018, 16: 791-801. 11. Jing-yi Fan, Ya-jie Fan, Xiang-ling Wang, Hong Xie, Hui-jie Gao, Yi Zhang, Min Liu, Hua Tang. miR-429 is involved in regulation of NF-κB activity by targeting IKKβ and suppresses oncogenic activity in cervical cancer cells. FEBS Lett. 2017, 591(1): 118-128. 12. Chang Liu*, Jinghua Wang*, Yang Hu, Hong Xie, Min Liu, Hua Tang. Upregulation of kazrin F by miR-186 suppresses apoptosis but promotes epithelial-mesenchymal transition to contribute to malignancy in human cervical cancer cells. Chin J Cancer Res. 2017, 29(1): 45-56. 13. Stefano Caramuta, Linkiat Lee, Deniz M. Özata, Pinar Akçakaya, Patrik Georgii-Hemming, Hong Xie, Rose-Marie Amini, Gunilla Enblad, Catharina Larsson, Mattias Berglund, Weng-Onn Lui. Role of microRNAs and microRNA machinery in the pathogenesis of diffuse large B-cell lymphomas. Blood Cancer J, 2013; 3: e152. 14. Stefano Caramuta, Linkiat Lee, Deniz M. Özata, Pinar Akçakaya, Hong Xie, Anders Höög, Jan Zedenius, Martin Bäckdahl, Catharina Larsson, Weng-Onn Lui. Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma. Endocr Relat Cancer, 2013; 20(4): 551-564. 15. Zhangsen Huang, Mohammed Ferdous-Ur Rahman, Lei Jiang, Hong Xie, Hu Hu, Weng-Onn Lui, Nailin Li. Thrombin induces de novo protein synthesis of stromal cell derive factor-1a but not angiostatin in human platelets. J Thromb Haemost, 2012; 10(10): 2202-2205. 16. Pinar Akçakaya, Susanne Ekelund, Iryna Kolosenko, Stefano Caramuta, Deniz M. Özata, Hong Xie, Ulrik Lindforss, Hans Olivecrona, Weng-Onn Lui. miR-185 and miR-133b deregulation is associated with overall survival and metastasis in colorectal cancer. Int J Oncol, 2011; 39(2): 311-318. 17. Deniz M.Özata*, Stefano Caramuta*, David Velázquez-Fernández, Pinar Akçakaya, Hong Xie, Anders Höög, Jan Zedenius, Martin Bäckdahl, Catharina Larsson, Weng-Onn Lui. The role of microRNA deregulation in the pathogenesis of adrenocortical carcinoma. Endocr Relat Cancer, 2011; 18(6): 643-655. *共同第一作者 #共同通讯作者。 ■ 主要著作 无 ■ 成果获奖情况 无 ■ 培养研究生要求 积极主动，诚实守信，勤于思考，勤奋刻苦，热爱科研工作，有较强的动手能力，有良好的团队合作意识。 |
